肼苯哒嗪引起狼疮综合征最常见的表现是关节痛、全身不适.也能引起皮肤红斑,但未见报导血管炎.作者遇见2例肼苯哒嗪引起皮肤溃疡性血管炎.现举1例:(例2略)患者女,63岁.因高血压病和持续肾损害15年于1977年9月服肼苯哒嗪,剂量增至250毫克/日时并用利尿剂、β-阻滞剂和甲基多巴.10个月后血清抗核抗体(ANA)阳性,效价1/40;一小时血沉33毫米.1979年7月ANA效价1/160;一小时血沉70毫 Hydralazine caused the most common manifestation of lupus syndrome is joint pain, malaise. Can also cause skin erythema, but no reported vasculitis. The authors met two cases of hydralazine caused by skin ulcerative vasculitis. Example: (Case 2 omitted) Female patient, aged 63. Hypertension and persistent renal impairment 15 years in 1977 September serving hydralazine dose to 250 mg / day and diuretics, β-block Agent and methyldopa. ANA positive after 10 months titer 1/40; one hour erythrocyte sedimentation rate 33 mm; ANA titer 1/160 in July 1979; one hour erythrocyte sedimentation rate 70 milliliters