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目的 :探讨环胞霉素A联合小剂量糖皮质激素和雄激素治疗再生障碍性贫血的临床价值。方法 :将 5 3例患者随机分成两组 ,治疗组 2 8例 ,用环胞霉素A配合小剂量泼尼松及康力龙治疗。对照组 ,2 5例用小剂量泼尼松及康力龙治疗。结果 :治疗组 :基本治愈 6例 ,缓解 8例 ,进步 8例 ,总有效率 78 6%;对照组 :基本治愈 3例 ,缓解 5例 ,进步 4例 ,总有效率为 48%,临床疗效治疗组优于对照组 (P <0 0 5 )。结论 :环胞霉素A联合小剂量糖皮质激素及雄激素治疗再生障碍性贫血 ,能明显提高疗效
Objective: To investigate the clinical value of cyclosporin A combined with low-dose glucocorticoid and androgen therapy for aplastic anemia. Methods: 53 patients were randomly divided into two groups, the treatment group 28 cases with cyclosporine A combined with low-dose prednisone and condinal treatment. In the control group, 25 patients were treated with low-dose prednisone and quetiapine. Results: In the treatment group, 6 cases were basically cured, 8 cases were alleviated and 8 cases were improved. The total effective rate was 78.6%. In the control group, 3 cases were basically cured, 5 cases were alleviated and 4 cases were improved. The total effective rate was 48% The treatment group was better than the control group (P <0 05). Conclusion: Cyclosporin A combined with low-dose glucocorticoid and androgen treatment of aplastic anemia can significantly improve the therapeutic effect