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目的:探讨非淋菌性尿道炎患者家庭儿童支原体与衣原体感染状况及耐药性。方法:选取2011年4月~2012年4月间来该院妇科、泌尿外科就诊的721户家庭,对入选家庭中803例儿童的泌尿生殖道标本进行支原体、衣原体检测,并检测患儿的支原体耐药性。结果:受检儿童中,共检出患儿66例,感染率为8.22%,女童感染率(10.10%)明显高于男童(6.39%),差异具有统计学意义(P<0.05);家庭和患儿解脲支原体(Uu)、人型支原体(Mh)、沙眼衣原体(Ct)的检出率呈正相关;Uu和Mh对患儿常用抗生素存在有不同程度的耐药性,其中克拉霉素、交沙霉素、环酯红霉素的耐药率明显偏低,差异具有统计学意义(P<0.05),罗红霉素、阿奇霉素的耐药率明显偏高,差异具有统计学意义(P<0.05)。结论:儿童非淋菌性尿道炎感染与父母之间呈明显正相关;女童支原体与衣原体感染率明显高于男童;Uu和Mh感染患儿对克拉霉素、交沙霉素、环酯红霉素的耐药率较低,对罗红霉素、阿奇霉素的耐药率较高。
Objective: To investigate the prevalence and drug resistance of mycoplasma and chlamydia in children with non-gonococcal urethritis. Methods: From July 2011 to April 2012, 721 families from gynecology department and urology department of our hospital were selected to test mycoplasma and chlamydia of genitourinary tract in 803 children in the selected families. Mycoplasma and mycoplasma Resistance. Results: 66 cases of children were detected, the infection rate was 8.22%, the infection rate of girls (10.10%) was significantly higher than that of boys (6.39%), the difference was statistically significant (P <0.05) There was a positive correlation between the detection rate of Uu and Mu and the prevalence of Uu, Mh and Ct in children. Uu and Mh had different degrees of resistance to commonly used antibiotics in children, among which clarithromycin , Jasamycin and erythromycin were significantly lower, the difference was statistically significant (P <0.05), and the drug resistance rates of roxithromycin and azithromycin were significantly higher (the difference was statistically significant ( P <0.05). Conclusion: The infection rate of non-gonococcal urethritis in children is positively correlated with that of parents. The prevalence of mycoplasma and chlamydia in girls is significantly higher than that in boys. The prevalence of clarithromycin, josamycin, Su-resistant rate is lower, the higher rates of resistance to roxithromycin, azithromycin.