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目的:探讨药物咨询与药物不良事件发生率的关系。方法:随机选取门诊内科和儿科复诊的1 069例患者或其家属进行问卷调查,探讨药物咨询与用药依从性、不良事件发生率的关系。结果:进行用药咨询和未进行用药咨询的不良事件标准化发生率分别为28.1%和50.8%;进行用药咨询组和未进行用药咨询组中用药依从性好的分别为76.0%和40.3%,二者差异有极显著性(P<0.01);用药依从性差和用药依从性好的患者不良事件发生率分别为56.2%和27.5%,二者差异有极显著性(P<0.01)。结论:通过用药咨询,促进合理用药,提高患者用药依从性,减少药物不良事件的发生。
Objective: To explore the relationship between drug counseling and the incidence of adverse drug reactions. Methods: A total of 1 069 patients or their relatives were selected randomly from outpatient department of internal medicine and pediatric clinic to investigate the relationship between drug counseling and drug compliance and incidence of adverse events. Results: The standardized rates of adverse events were 28.1% and 50.8%, respectively, with and without medication counseling; 76.0% and 40.3% were good in medication counseling group and no medication counseling group, respectively; both The difference was significant (P <0.01). The incidences of adverse events were 56.2% and 27.5% respectively in patients with poor medication compliance and medication adherence, the difference was significant (P <0.01). Conclusion: Through the medication counseling to promote the rational use of drugs to improve patient compliance and reduce the incidence of adverse drug events.