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本文采用ＨＰＶＤＮＡ原位分子杂交法检测了３０例尖锐湿疣组织标本，结果显示ＨＰＶ６／１１型阳性检出率为８６．６％，ＨＰＶ１６／１８型为１６．６％，ＨＰＶ３１／３３／３５则为阴性，总的阳性检出率为９０％。阳性结果除见于表皮浅层外，还见于棘细胞层中下部及基底细胞层内。作者认为原位分子杂交法是目前检测ＨＰＶ感染及其分型的一种敏感、特异、快速且相对简便的方法，又能进行感染的组织学定位，同时这一方法还适应于对以往病例进行回顾性调查。
In this paper, HPVDNA in situ hybridization was used to detect 30 cases of condyloma acuminata tissue samples, the results showed that HPV6 / 11 positive rate was 86.6%, HPV16 / 18 type was 16.6%, HPV31 / 33/35 was Negative, the total positive detection rate was 90%. In addition to the positive results found in the superficial epidermis, but also found in the lower part of the spinous cell layer and basal cell layer. The authors believe that in situ hybridization is a sensitive, specific, rapid and relatively simple method for detection of HPV infection and its classification, but also for the histological localization of infection, and this method is also adapted to the previous cases Retrospective survey.