破伤风类毒素的自动免疫,在国内外已被广泛的采用。根据氏等著“急性传染病学教程”纪载,施行此种接种(注1),可发生一系列的局部和全身性反应。局部反应为紧张、发热、红肿疼痛、发痒及邻近的淋巴结肿大等。全身性反应为周身不适、关节痛、发烧、腹泻、呕吐及少见的过敏性休克等。我部在1958年施行破伤风类毒素(注2)免疫注射中,因类毒素的接种,而引起过敏性紫斑2例(但因材料不足,本文只报告1例)。因破伤风类毒素的接种而引起该症者,尚属罕见,故加以整理,报导于后。病例报告蒋××,21岁,男性,于1958年4月7日入卫生連。主诉:两下肢疼痛肿胀、出疹子、发痒已十余天。患者于3月27日中午,行破伤风类毒素免疫注射(0.5毫升,皮下注入)。当日下午感两下肢发痒,次日晨发现左小腿前内侧有十余个帽针头大小的鲜红色斑。右小腿亦旋即发生,迅速向上蔓延至 Tetanus toxoid autoimmunity has been widely adopted both at home and abroad. According to Ji’s Acute Infectious Diseases Tutorial, a series of local and systemic reactions can occur as a result of such vaccination (Note 1). Local reactions are intense, fever, swelling and pain, itching and adjacent lymph nodes and so on. Systemic reaction for the whole body discomfort, joint pain, fever, diarrhea, vomiting and rare anaphylactic shock. In our immunization with tetanus toxoid (Note 2) in 1958, our department caused 2 cases of allergic purpura due to toxoid inoculation (only one case was reported due to lack of materials). Due to tetanus toxoid inoculation caused the disease, is still rare, it is to be arranged, reported later. Case report Chiang × ×, 21 years old, male, on April 7, 1958 into health even. Chief Complaint: Two lower limb pain swelling, rash, itching has more than ten days. Patients were immunized with tetanus toxoid (0.5 ml, injected subcutaneously) at noon on March 27. On the afternoon of the two legs feel itchy afternoon, the morning before the discovery of the left leg has more than a dozen cap needle size red spots. The right leg also occurs immediately, quickly spread to