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Dear Editor,rnCarriers of balanced chromosomal rearrangements,including reciprocal,robertsonian translocations,and inversions,have all genetic information conserved.Nevertheless,because of the possibility of defect in chromosome segregation during gametogenesis,carriers ofbalanced rearrangements have an increased risk of spontaneous abortion and/ or a chromosomally unbalanced child with intellectual deficiency or multiple congenital malformations.Unbalanced translocations in patients with normal phenotype are rarely described.Only three unbalanced translocations involving acrocentric chromosome with meiotic defects were reported in the literature in infertile men.1-3