米托蒽醌聚乳酸缓释毫微粒冻干针剂的体外释药特性研究

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选择含1%维生素C的生理盐水作释药介质,用动态透析系统和分光光度法考察了不同分子量聚乳酸毫微粒冻干针剂的体外释药特性。分离子量聚乳酸毫微粒的释药速度明显慢于低分子量的聚乳酸毫微粒。通过选择适应分子量的聚乳酸制备毫微粒可控制其释药速度。
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