胖大海属梧桐科落叶乔木,药用成份为其成熟的种子,具有开肺气,清肺热、润肠通便之功效,临床用于肺热声哑、咽喉疼痛、痰热咳嗽等症.近来有不少饮料厂家以胖大海为主要原料开发出保健饮料,在市场上颇受欢迎.为科学地评价此种饮料对人体的安全性,我们依据《食品安全性毒理学评价程序和方法》,对胖大海饮料进行了第一、二阶段的毒性试验,对其急性毒性和致突变性进行了研究. Fat sea is a deciduous tree Indus floor, medicinal ingredients for its mature seeds, with open lung qi, clear lung heat, laxative effects, clinically used for Hyperactivity dumb, sore throat, phlegm cough embolism. Recently, many beverage manufacturers have developed health drinks based on fat and sea as the main raw materials, and are very popular on the market. To scientifically evaluate the safety of such beverages on human beings, we have formulated the “Safe Food Toxicology Evaluation Program and Methods” , Conducted the first and second phase toxicity test on the fat sea drink, and studied its acute toxicity and mutagenicity.