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多形性室性心动过速(多形性室速)即尖端扭转型室速,常发生于用药后(特别是Ⅰ类抗心律失常药)。本文报导五例在用乙胺碘呋酮后引起多形性室速而致晕厥或意识丧失。所有病例在用药后均有QT间期延长,其中两例伴有低血钾,但在纠正低血钾后未能消除多形性室速。五例病人均用异丙基肾上腺素,临时心室起搏,或两者同时进行而抢救成功。
Polymorphic ventricular tachycardia (pleomorphic VT) that is torsades de pointes, often occurs after treatment (especially class Ⅰ antiarrhythmic drugs). This article reports five cases of amiodarone caused by polymorphic VT-induced syncope or loss of consciousness. In all cases, the QT interval was prolonged after treatment, of which two had hypokalemia, but failed to eliminate pleomorphic VT after correcting for hypokalemia. Five patients were treated with isoproterenol, temporary ventricular pacing, or both at the same time.