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我院自1997年1月至1998年6月共收治重度有机磷中毒患者40例,其中伴自主呼吸停止8例,全部抢救成活。1 临床资料女24例,男16例,年龄16～67岁,平均31.2岁,均为口服中毒。农药种类:甲胺磷28例,氧化乐果6例,乐果3例,敌敌畏3例,服毒量50～250ml不等。8例病人在服毒后30分钟至12小时内自主呼吸停止,随即以气管插管救治。40例患者均属重度中毒,入院时测血胆碱脂酶均小于5u。经急诊洗胃,部分病人行血液灌流,及拮抗剂、解毒剂、机械通气等使用后,病人全部存活。阿托品最小用量340mg,最大用量11 342mg。病程最短11天,最长35天。
Our hospital from January 1997 to June 1998 were treated severe organophosphate poisoning in 40 patients, including spontaneous breathing in 8 cases, all rescued and survived. 1 clinical data of 24 females, 16 males, aged 16 to 67 years, mean 31.2 years old, are oral poisoning. Pesticide types: Methamidophos 28 cases, omethoate 6 cases, dimethoate 3 cases, dichlorvos 3 cases, the dose of 50 ~ 250ml range. 8 patients in the poisoning after 30 minutes to 12 hours of spontaneous breathing stopped, followed by tracheal intubation. All 40 patients were severe poisoning. Blood cholinesterase levels were less than 5u at admission. After emergency gastric lavage, some patients underwent hemoperfusion, and antagonists, antidotes, mechanical ventilation and other use, the patient all survived. Atropine minimum dosage 340mg, the maximum amount of 11 342mg. The shortest duration of 11 days, up to 35 days.