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为观察江西省现阶段儿童乙型肝炎 (乙肝 )病毒 (HBV)感染状况及影响因素 ,于 2 0 0 2年 10~ 12月采用多阶段整群抽样法 ,抽取 10个样本 ,10 12名 1994年 1月 1日~ 2 0 0 1年 12月 31日出生 (1~ 8岁 )的儿童 ,用固相放射免疫法 (SPRIA)检测HBV感染的基本指标 :乙肝病毒表面抗原 (HBsAg)与抗体 (抗 HBs)、乙肝病毒核心抗体 (抗 HBc)。结果显示 :HBsAg流行率为 8 89% ,抗 HBs流行率为 74 6 0 % ,抗 HBc流行率为 10 87%。HBsAg和抗 HBc流行率均是农村高于城市 (P <0 0 1) ,抗 HBs流行率城市高于农村 (P <0 0 1)。乙肝疫苗接种、母亲HBsAg阳性的儿童乙肝疫苗首针在 2 4h内接种与HBsAg、抗 HBc流行率成负相关 ,儿童出生前母亲HBsAg阳性则与之呈正相关。
To observe the current status of hepatitis B virus (HBV) infection in children in Jiangxi Province and its influencing factors, a multistage cluster sampling method was adopted from October to December 2002 to select 10 samples and 10 12 patients Children born between January 1 and December 31, 2001 (aged 1 to 8 years old) were tested for the basic indicators of HBV infection by solid-phase radioimmunoassay (SPRIA): hepatitis B virus surface antigen (HBsAg) and antibodies Anti-HBs), hepatitis B virus core antibody (anti-HBc). The results showed that the prevalence of HBsAg was 8 89%, the anti-HBs prevalence was 74 60%, and the anti-HBc prevalence was 10 87%. The prevalence of HBsAg and anti-HBc were higher in rural than in urban (P <0.01), and the prevalence of anti-HBs in urban was higher than that in rural (P <0.01). Hepatitis B vaccination, mother HBsAg-positive children with hepatitis B vaccine inoculation within 24 hours and HBsAg, anti-HBc prevalence rate is negatively correlated, before the birth of mothers HBsAg positive children with a positive correlation.