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作者选用一剂量较大青霉素(30万 u/kg)静滴,继以复力新诺明针剂(每支含 SMZ 400mgTMP80mg)按 SMZ40～50mg/kg/d,分次每隔12小时溶于125ml,5%葡萄糖液中静滴(病情稳定改肌注)治疗脑膜炎12例,并于用药后48小时测定血及脑脊液中复方新诺明的浓度。12例均为18个月～12岁之普通型流脑患儿。除1例在用药48小时仍有高热与脑膜刺激症,改用青霉毒外,余11例顺利治愈。退热平均25小时,克氏征平均32.2小时、颈抗平均36.7小时恢复,脑脊液于用药48小时后,细胞数明
The author selected a larger dose of penicillin (300,000 u / kg) intravenous infusion, followed by ciclosporin (each containing SMZ 400mgTMP80mg) by SMZ40 ~ 50mg / kg / d, every 12 hours dissolved in 125ml , Intravenous infusion of 5% glucose solution (stable condition intramuscular injection) treatment of meningitis in 12 cases, and 48 hours after treatment measured blood and cerebrospinal fluid cotrimoxazole concentration. 12 cases were 18 months to 12 years old ordinary meningitis in children. In addition to one case of medication in 48 hours there are still high fever and meningeal irritation, switch to penicillin, the remaining 11 cases were cured. An average of 25 hours of antipyretic, Kirschner sign an average of 32.2 hours, the average anti-neck 36.7 hours recovery, cerebrospinal fluid 48 hours after treatment, the number of cells