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目的 :了解医院下呼吸道嗜麦芽窄食单胞菌 (S .m )感染的危险因素及耐药情况。方法 :对 3 4例S .m下呼吸道感染的临床资料进行回顾性分析。结果 :高龄、长期住院、患严重基础疾病、侵入性诊疗操作、长期应用广谱抗生素为其危险易感因素。药敏试验结果显示 :替卡西林 /克拉维酸的敏感性在 69 0 % ,环丙沙星的敏感率为 5 2 3 % ,氨基糖苷类及大多数 β 内酰胺类普遍耐药。结论 :S .m已成为医院内下呼吸道感染的致病菌之一。有易感因素时 ,应密切注意S .m感染的发生 ,一旦感染 ,可选用抗菌药物范围较窄 ,治疗应根据药敏 ,及时、足量、联合使用有效抗生素
Objective: To understand the risk factors and drug resistance of lower respiratory tract Stenotrophomonas maltophilia in hospital. Methods: The clinical data of 34 cases of S .m lower respiratory tract infection were retrospectively analyzed. Results: The elderly, long-term hospitalization, suffering from serious underlying diseases, invasive diagnosis and treatment of long-term use of broad-spectrum antibiotics as risk predisposing factors. Susceptibility test results showed that the sensitivity of ticarcillin / clavulanic acid was 69 0%, the sensitivity of ciprofloxacin was 52.3%, and aminoglycosides and most β-lactams were generally resistant. Conclusion: S.m has become one of the pathogens of lower respiratory tract infection in hospitals. There are susceptibility factors, should pay close attention to the occurrence of S. M infection, once infected, antibiotics can choose a narrower range, the treatment should be based on drug sensitivity, timely and adequate use of effective antibiotics