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目的探讨肌电引导对提高Ａ型肉毒素局部注射治疗颈部肌张力障碍的有效性和安全性。方法对３２例颈部肌张力障碍患者采用交叉对照设计，分成肌电引导和非肌电引导注射组。注射Ａ型肉毒素的部位和剂量，根据受累肌肉、大小及痉挛、肥厚程度。按Ｔｓｕｉ量表评价疗效。结果肌电引导组和非肌电引导组比较，治疗前后评分减少分别为１１．５３±３．４１和１０．８４±３．２５，ｔ＝２．６４，Ｐ＜０．０５；明显和基本缓解率分别为８４％和７５％；颈肌无力和吞咽困难副作用分别为３例（９．３６％）和９例（２８．１３％），χ２＝４．１７，Ｐ＜０．０５；２～７周完全恢复。结论该方法可明显提高颈部肌张力障碍的疗效及减少副作用。
Objective To investigate the efficacy and safety of myoelectricity guidance in improving the treatment of cervical dystonia by topical injection of botulinum toxin type A. Methods A total of 32 patients with cervical dystonia were divided into two groups: control with electromyography and non-electromyography. The site and dose of botulinum toxin type A is injected, depending on the muscle involved, size and cramps, and the degree of hypertrophy. By Tsui scale evaluation of efficacy. Results Compared with the non-myoelectricity guide group, the scores of myoelectricity-guided group and the non-myoelectricity-guided group were 11.53 ± 3.41 and 10.84 ± 3.25, respectively, t = 2.64, P <0.05; The rates of remission were 84% and 75% respectively. The side effects of cervical muscle weakness and dysphagia were 3 cases (9.36%) and 9 cases (28.13%) respectively, χ2 = 4.17, P <0.05; 2 ~ 7 weeks to fully recover. Conclusion This method can significantly improve the efficacy of cervical dystonia and reduce side effects.