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主要的血管扩张剂前列腺素是PGI_2和PGE_2，主要的血管收缩剂是血栓素A_2（TxA_2），而白三烯是花生四烯酸代谢中另一个强力的血管活性产物。注人鼠体内，半胱氢酞白三烯C_4（LTC_4）引起内脏和冠状动脉收缩，出l现类似休克的症状和体征。LTC_4在急性出血／再灌注损伤后内脏循环的作用不清楚。本实验观察轻度出血／再灌注损伤时内源性内脏二十烯酸在介导LTC_4引起内脏血管收缩的作用。制备鼠休克模型，取SD雄
The main vasodilator prostaglandins are PGI 2 and PGE 2, the major vasoconstrictor is thromboxane A 2 (TxA 2), and leukotriene is another potent vasoactive product of arachidonic acid metabolism. Into the mouse, cysteamine hydrogenated C_4 (LTC_4) caused visceral and coronary contractions, out of l are similar to the symptoms and signs of shock. The role of LTC_4 in visceral circulation after acute hemorrhage / reperfusion injury is unclear. This experiment observed the endogenous visceral eicosanoid in mediating LTC_4 induced vasoconstriction during mild hemorrhage / reperfusion injury. Preparation of rat shock model, take SD male