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目的:探讨烧伤再生疗法(BRT)和湿润烧伤膏(MEBO)治疗烧伤的临床效果。方法:该试验为前瞻性、单一中心临床研究,研究对象为2009年9月和2010年3月间筛选出的10名年龄在3个月至75岁之间的浅Ⅱ度～Ⅲ度烧伤患者,全程采用BRT和MEBO治疗,观察记录创面75%愈合时间、创面100%愈合时间、创面感染率、疼痛指数、平均住院时间、过敏反应率,并拍摄照片进行治疗前后的对比观察。结果:创面75%和100%愈合的平均时间分别为27.3天和59.0天;换药时的平均疼痛指数为4;住院时间最短9天,最长151天,平均住院时间为57.1天;细菌感染率为10%;没有发现过敏反应。结论:在本研究中,有些创面本是需要接受植皮手术的,但是经MEBO继续治疗4周～6周后能够成功实现上皮化再生愈合。因此,MEBO治疗烧伤的有效性毋庸置疑。
Objective: To investigate the clinical effects of burns regeneration therapy (BRT) and MEBO treatment of burns. METHODS: This trial was a prospective, single-center clinical study of 10 patients with superficial to moderate-grade burns between the ages of 3 months and 75 years screened between September 2009 and March 2010 , The whole course of treatment with BRT and MEBO, observed and recorded wound healing time of 75%, wound healing time of 100%, wound infection rate, pain index, average length of stay, anaphylactic reaction rate, and take photographs for comparison before and after treatment. Results: The mean time to heal wound healing at 75% and 100% was 27.3 days and 59.0 days, respectively. The mean pain index was 4. The shortest hospital stay was 9 days, the longest was 151 days, and the average hospital stay was 57.1 days. The bacterial infection Rate was 10%; no allergic reaction was found. CONCLUSIONS: In this study, some wounds were originally treated for skin grafting. However, MEBO continued treatment for 4 to 6 weeks to successfully regenerate epithelialized wounds. Therefore, the effectiveness of MEBO in the treatment of burns is beyond doubt.