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关于恶性淋巴瘤骨髓移植的状况是复杂的,加上疾病本身的多样性,近年陆续出现了强有力的化学疗法,最近,由于 G-CSF、GM—CSF 这样强有力的血细胞刺激因子又可用于治疗淋巴系肿瘤,可能会使化学疗法方案发生大的变化。随着这种变化,治愈率也在提高,将使骨髓移植的地位变得不明确。另外,强烈的化疗,危险性也自然上升,根据各治疗单位的状况不同,可以实施的方案不尽相同,实际治愈率的幅度大有扩展的倾向,因此正处于难以建立统一的治疗策略的状态之中。本文在于讨论在恶性淋巴瘤治疗中骨髓移植的作用,兼论述目前作者的治疗策略。
With regard to the situation of malignant lymphoma bone marrow transplantation is complex, coupled with the diversity of the disease itself, in recent years, there has been a strong chemotherapy, and recently, due to G-CSF, GM-CSF such a powerful blood cell stimulating factor in turn Treatment of lymphoid tumors may cause major changes in chemotherapy regimens. With this change, the cure rate is also rising, which will make the status of bone marrow transplantation unclear. In addition, the strong chemotherapy and the risk of natural increase, according to the treatment of different units, can implement the program is not the same, the actual rate of cure tends to greatly expand the tendency, it is difficult to establish a unified treatment strategy state Among them. This article addresses the role of bone marrow transplantation in the treatment of malignant lymphoma and discusses the current author’s strategy for treatment.