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目的:系统评价清开灵注射液用于呼吸系统感染的临床疗效。方法:利用RevMan5.0软件对国内1994-2008年发表的运用清开灵注射液治疗呼吸系统感染的临床对照试验进行Meta分析,对不同纳入标准的研究结果进行了敏感度分析。结果:疗效评价共纳入22个临床对照试验研究,采用固定效应模型计算,清开灵注射液治疗呼吸系统感染的效应值OR=4.38,95%置信区间为[3.28,5.85]。结论:清开灵注射液对呼吸系统感染的治疗与对照组相比,疗效可能优于对照组。
Objective: To systematically evaluate the clinical efficacy of Qingkailing injection for respiratory infections. Methods: The RevMan5.0 software was used to conduct a meta-analysis of the clinical control trials of Qingkailing injection for respiratory infections published in China during 1994-2008. Sensitivity analysis was conducted on the results of different inclusion criteria. Results: A total of 22 clinical trials were included in the evaluation of efficacy. The effect of Qingkailing Injection on respiratory infection was calculated using the fixed effect model. OR = 4.38, 95% confidence interval [3.28,5.85]. Conclusion: The Qingkailing injection treatment of respiratory infections compared with the control group, the effect may be better than the control group.