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芬兰Wuorimaa等报告 ,11价混合载体肺炎链球菌结合疫苗对婴幼儿是安全的 ,并有免疫原性。 (PediatrInfectDisJ 2 0 0 0 ,2 0 :2 72 )肺炎链球菌多糖疫苗对于 2岁以上的儿童是有免疫原性的 ,但是在小婴幼儿效果受限。结合疫苗可克服多糖疫苗的免疫原性
Finland Wuorimaa et al reported that 11 mixed vector pneumococcal conjugate vaccine is safe for infants and young children and is immunogenic. (Pediatr Infect Disj 0 2000, 2 0: 2 72) The S. pneumoniae polysaccharide vaccine is immunogenic for children over 2 years of age, but has limited effectiveness in young infants. The combination of vaccines can overcome the immunogenicity of the polysaccharide vaccine