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1963年Galton等提出幼稚淋巴细胞白血病(PLL)一词,并于1974年报道了15例,规定了比较精确的有关这种病的形态学标准。据此,PLL是一种临床病理学上独立的疾病,来源于单克隆性B-或T-细胞。其特点是脾脏肿大,淋巴结不肿大或稍肿大,白细胞明显增加,其中有大量幼稚淋巴细胞。Galton和Enno等认为这些临床病理学特征不同于典型慢淋,慢淋的幼稚淋巴细胞转化型、淋巴肉瘤细胞白血病及急性原始淋巴细胞白血病。本文报道5例PLL病染色体
In 1963, Galton et al. Proposed the term naive lymphocytic leukemia (PLL), and in 1974, reported 15 cases, providing a more accurate morphological criteria for the disease. Accordingly, PLL is a clinically pathologically independent disease derived from monoclonal B- or T-cells. It is characterized by enlarged spleen, lymph nodes are not swollen or slightly swollen, significantly increased white blood cells, including a large number of naive lymphocytes. Galton and Enno et al. (2001) consider these clinicopathological features to be different from those of typical chronic lymphocytic leukemia, lentivirus leukemia and acute lymphoblastic leukemia. This article reports 5 cases of PLL chromosomes