本文对49例进行性肌营养不良症(PMD)中的DMD、LG、FSH三型进行了血清CPK、LDH、GOT及GPT四种酶活性测定与分析。结果在PMD中的四种酶以CPK活性升高最为显著,其中DMD型的CPK活性显著高于正常对照组、神经元性疾病组(P<0.001),其升高率为100％;DMD型的CPK活性也显著高于LG与FSH型(P<0.05,P<0.01)。说明血清CPK活性的测定可作DMD型诊断中一项灵敏而实用的酶学指标,对DMD与神经无性疾病以及LG、FSH两型肌病的鉴别诊断也有一定的临床应用价值。 In this paper, 49 cases of progressive muscular dystrophy (PMD) in the DMD, LG, FSH type of serum CPK, LDH, GOT and GPT four enzyme activity measurement and analysis. Results The four enzymes in PMD showed the most significant increase in CPK activity. The CPK activity in DMD group was significantly higher than that in normal control group and neuronal disease group (P <0.001) CPK activity was also significantly higher than LG and FSH type (P <0.05, P <0.01). It indicates that the determination of serum CPK activity can be used as a sensitive and practical enzymological index in the diagnosis of DMD. It also has certain clinical value in the differential diagnosis of DMD and neurological aseurosis and LG and FSH type II myopathy.