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目的探讨单纯应用异丙酚与异丙酚+阿托品和单纯应用笑气与笑气联合米索前列醇对无痛人工流产术后阴道出血时间的影响。方法随机选择400例早孕自愿要求进行无痛人工流产术者,将400例孕妇随机分为4组每组100人,异丙酚+阿托品组在静推异丙酚之前静推阿托品;异丙酚组直接静脉推注异丙酚注射液;笑气联合米索前列醇组在术前2小时空腹口服米索前列醇,术中给予笑气吸入;笑气组仅在术中给与笑气吸入。结果异丙酚+阿托品组和异丙酚组比较(χ2=0.4134,P<0.05)有显著差异,笑气联合米索前列醇组和笑气组比较有显著差异(χ2=14.22,P<0.05),异丙酚+阿托品组和笑气联合米索前列醇组比较两组有显著差异(χ2=4.7138,P<0.05)。结论无痛人工流产术前加用阿托品或米索前列醇,这两种方法弥补了单纯静脉麻醉和吸入麻醉的不足,缩短了术后阴道出血时间,在这4种方法中笑气联合米索前列醇在缩短无痛人工流产术后阴道出血时间效果最佳。
Objective To investigate the effect of simple propofol and propofol + atropine and simple application of nitroglycerin combined with misoprostol on vaginal bleeding after painless artificial abortion. Methods A total of 400 pregnant women were enrolled in the study. One hundred and four pregnant women were randomized into four groups of 100 patients randomly. Propofol and atropine groups were given atropine exactly before propofol bolus. Propofol Group was injected intravenously with propofol injection. The nitrous oxide combined with misoprostol group was orally administered with misoprostol 2 hours before operation, while nitrous oxide was given intraoperatively. . Results There was significant difference between propofol + atropine group and propofol group (χ2 = 0.4134, P <0.05), and there was significant difference between nifedipine + misoprostol group and noxious group (χ2 = 14.22, P <0.05 ), Propofol + atropine group and nitrous oxide combined misoprostol group there was significant difference between the two groups (χ2 = 4.7138, P <0.05). Conclusion Painless abortion plus atropine or misoprostol before surgery, these two methods to make up for the lack of pure intravenous anesthesia and inhalation anesthesia, shortened the postoperative vaginal bleeding time, in these four methods combined with nitrous oxide gas Epoprostenol in the shorten the painless artificial abortion postoperative vaginal bleeding the best time.