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目的探讨糖化血红蛋白(HbA1c)与超敏C-反应蛋白(hs-CRP)水平与2型糖尿病患者肺通气功能改变的关系。方法选取56例2型糖尿病患者为病例观察组,另选80名健康人为对照组。病例组根据并发症分为2组,A组无并发症,B组2型糖尿病合并微血管并发症,全部被选人员均用肺功能检测仪测定肺功能,并于清晨空腹取静脉血测定HbA1c与hs-CRP。结果 B组HbA1c与血清中hs-CRP水平明显高于A组,与肺通气功能改变呈负相关趋势。结论 HbA1c与hs-CRP对了解2型糖尿病患者病情以及患者肺通气功能改变有重要的意义。
Objective To investigate the relationship between the levels of HbA1c and hs-CRP in patients with type 2 diabetes and the changes of pulmonary ventilation. Methods Fifty-six patients with type 2 diabetes mellitus were selected as observation group and 80 healthy people as control group. The cases were divided into two groups according to the complication: group A without complication; group B with type 2 diabetes mellitus and microvascular complication; all the selected persons were tested for pulmonary function by pulmonary function test instrument and HbA1c hs-CRP. Results The levels of HbA1c and serum hs-CRP in group B were significantly higher than those in group A, and negatively correlated with the change of pulmonary ventilation. Conclusion HbA1c and hs-CRP are important in understanding the condition of patients with type 2 diabetes mellitus and the changes of pulmonary function in patients.