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目的探讨加替沙星致不良反应的一般规律和临床特点,为临床合理用药提供参考。方法对近5年来我院用加替沙星致不良反应20例患者进行分类统计、分析。结果不良反应临床表现为胃肠道反应、神经系统反应、糖代谢异常及皮肤过敏反应,且老年患者的发生率较高。结论临床需重视加替沙星的抗菌效应和不良反应的危害性。
Objective To investigate the general and clinical features of gatifloxacin-induced adverse reactions and provide a reference for clinical rational drug use. Methods 20 cases of adverse reactions caused by gatifloxacin in our hospital in the past 5 years were classified and analyzed. Results The clinical manifestations of adverse reactions were gastrointestinal reactions, nervous system reactions, abnormal glucose metabolism and skin allergic reactions, and the incidence of elderly patients was higher. Conclusion The clinical need to pay attention to the antimicrobial effect of gatifloxacin and adverse reactions.