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目的分析药品不良反应(ADR)的情况及发生特点,为临床安全用药提供参考。方法对商丘市中心医院2004年1月—2009年12月发生的102例药品不良反应(ADR)进行回顾性分类与统计分析。结果 102例ADR共涉及药品48种,静脉给药途径所引发的ADR最多,抗感染药占38.24%;中药制剂占30.40%。结论抗感染药、中药制剂ADR的发生率高。提醒临床应密切关注药品ADR,加强药品ADR的监测与上报工作,合理规范使用药物,减少ADR的发生率。
Objective To analyze the situation and characteristics of adverse drug reaction (ADR) and provide references for clinical safety medication. Methods A retrospective classification and statistical analysis of 102 adverse drug reactions (ADR) occurred in Shangqiu Central Hospital from January 2004 to December 2009 were performed. Results A total of 102 ADRs were involved in 48 kinds of drugs. The most ADRs were caused by intravenous route of administration, anti-infectives accounted for 38.24% and traditional Chinese medicines accounted for 30.40%. Conclusion Anti-infectives and traditional Chinese medicine preparations have a high incidence of ADR. To remind the clinical should pay close attention to drugs ADR, drug monitoring and reporting of ADR to strengthen the work, rationalize the use of drugs, reduce the incidence of ADR.