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目的怒江峡谷海拨1 600m以下均属疟疾流行地区,年均发病数在600例以上;发病以间日疟疾为主;为防止部分间日疟疾病人休止期根治中因G6PD缺乏,服用伯氨喹啉片后产生溶血,怒江州疾病预防控制中心及所属泸水、福贡、贡山县疾病预防控制中心在2010年1~6月份,休止期根治前对上一年有疟史的人开展了G6PD缺乏筛查工作。方法红细胞葡萄糖-6-磷酸脱氢酶(G6PD)活性筛查试剂盒(纯化学反应荧光法)。结果共筛查2009年有疟史者412人;其中有强荧光反应的357人(G6PD不缺乏),弱荧光反应的44人(轻、中度缺乏),无荧光反应的11人(重度缺乏)。结论以此为依据,对G6PD缺乏者不再作为休根对象,为我州顺利完成休止期根治任务提供了技术保障。
Objective Nujiang Valley below 1,600 m above sea level are malaria-endemic areas, with an average annual incidence of more than 600 cases; the incidence of malaria-based in the intervenous days; in order to prevent part of the malaria patients due to lack of G6PD during the rest period, taking primaquine Haemophilus after hemolysis, Nujiang Center for Disease Control and its affiliated Lushui, Fugong, Gongshan County Center for Disease Control and Prevention in 2010 1 ~ 6 months, the rest period before the start of a previous history of malaria were carried out G6PD lack of screening. Methods Erythrocyte glucose-6-phosphate dehydrogenase (G6PD) activity screening kit (pure chemical reaction fluorescence method). Results A total of 412 malaria patients were screened in 2009, including 357 patients with strong fluorescence (G6PD deficiency), 44 patients with mild fluorescence (mild to moderate deficiency) and 11 patients without fluorescence reaction (severe hypothyroidism ). Conclusion Based on this, G6PD deficiency is no longer regarded as the object of rest, which provides technical support for the successful completion of the restful period cure task in our country.