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目的探讨糖化血红蛋白(HbA1c)联合纤维蛋白原(FIB)检测在2型糖尿病(T2DM)眼部微血管病变诊断价值。方法检测T2DM合并眼部微血管病变(A组)及眼部无微血管病变患者(B组)HbA1c及FIB水平并统计学分析。结果 A组HbA1c和F1B明显高于B组,两组有统计学差异(P<0.05);A组中HbA1c及FIB呈正相关,且明显高于B组(P<0.05)。HbA1c单项检测低于两者联合检测阳性率(P<0.05)。结论联合检测HbA1c和FIB对于早期诊断和治疗T2DM合并眼部微血管病变有重要价值。
Objective To investigate the diagnostic value of HbA1c combined with fibrinogen (FIB) in the diagnosis of ocular microangiopathy in type 2 diabetes mellitus (T2DM). Methods The levels of HbA1c and FIB in patients with T2DM complicated with ocular microangiopathy (group A) and those without ocular microangiopathy (group B) were detected and statistically analyzed. Results The levels of HbA1c and F1B in group A were significantly higher than those in group B (P <0.05). There was a positive correlation between HbA1c and FIB in group A and significantly higher than that in group B (P <0.05). The single detection of HbA1c was lower than the positive rate of both (P <0.05). Conclusion Combined detection of HbA1c and FIB is of great value in the early diagnosis and treatment of T2DM complicated with ocular microangiopathy.