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为了研究食用蛋白质和氨基酸变异后的热分解物的致癌作用,以摄取烤鱼为中心进行了分析流行病学研究。研究对象是曾在1968～1970年3年间在广岛和长崎用于其他研究而做过有关饮食习惯等方面调查的11,203人,其中四分之三是原子弹受害者。11,203人中有7,553人保留着过去调查的关于年龄,性别,核辐射线量,学历,吸烟习惯,食用烤鱼、鱼干、牛奶、腌渍物、水果、米饭的习惯程度等11项记录。对这些人进行追踪观察约11年,根据户口确认了至1978年12月的生死情况,并根据保健所提供的资料调查了死者的死因。调查结果表明,摄取烤鱼的次数在每周2次以上者,与低于这个次数者相比,患癌症的危险性为1.3倍
In order to study the carcinogenic effects of pyrolytic substances after eating protein and amino acid variation, an epidemiological study was conducted focusing on ingestion of grilled fish. The subjects were 11,203 people who had conducted surveys on dietary habits such as Hiroshima and Nagasaki between 1968 and 1970 for other studies, of which three-fourths were victims of the atomic bomb. Of the 11,203 people, 7,553 kept 11 records of past surveys on age, sex, radiation levels, education, smoking habits, consumption of grilled fish, dried fish, milk, pickles, fruits and rice. After about 11 years of follow-up observation of these people, the life and death status as of December 1978 was confirmed on the basis of registered permanent residence and the cause of death of the deceased person was investigated on the basis of information provided by the health clinic. The survey showed that the number of fish caught more than 2 times per week, compared with those less than 1.3 times the risk of cancer