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[Objective] To research on the anti-inflammatory effects of CORTEX PHELLODENDRI in acute inflammation animal model.[Methods]Two acute inflammation animal models were established,including the auricle swelling test model of mice induced by xylene,and the abdominal capillary permeability model of mice induced by 1% glacial acetic acid. The anti-inflammatory effects of CORTEX PHELLODENDRI were observed. [Results]CORTEX PHELLODENDRI had different inhibitory effects on the auricle swelling of mice induced by xylene,and the abdominal capillary permeability of mice induced by 1% glacial acetic acid. The alkaloid part had significant differences with model group(P < 0. 05 or P < 0. 01). [Conclusions]Alkaloid part had good anti-inflammatory effects; while the effects of n-butanol,ethyl acetate,chloroform and petroleum ether parts were in different degrees.
[Objective] To research on the anti-inflammatory effects of CORTEX PHELLODENDRI in acute inflammation animal model. [Methods] Two acute inflammation animal models were established, including the auricle swelling test model of mice induced by xylene, and the abdominal capillary permeability model of The results from CORTEX PHELLODENDRI had different inhibitory effects on the auricle swelling of mice induced by xylene, and the abdominal capillary permeability of mice induced by 1% The alkaloid part had significant differences with model group (P <0.05 or P <0.01). [Conclusions] Alkaloid part had good anti-inflammatory effects; while the effects of n-butanol, ethyl acetate, chloroform and petroleum ether parts were in different degrees.