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目的:探讨1986～2006年福建省围产儿出生缺陷的特征与变化趋势,为出生缺陷的预防和干预提供科学依据。方法:收集福建省出生缺陷监测医院1986～2006年出生和引产的孕28周至产后7天的6397例围产儿出生缺陷资料,出生缺陷总发生率为11.3‰,分析出生缺陷特征别发生率、顺位和长期趋势。用卡方检验和时间序列分析等统计学方法分析出生缺陷的发生特征、变化趋势。结果:1986～2006年福建省出生缺陷发生率呈现逐年升高的趋势(趋势χ2=5.708,P<0.05)。出生缺陷分布有明显的季节聚集性。结论:福建省出生缺陷发生率呈上升趋势。
Objective: To explore the characteristics and trends of birth defects in perinatal infants from 1986 to 2006 in Fujian province, and to provide a scientific basis for the prevention and intervention of birth defects. Methods: A total of 6397 cases of perinatal infants with birth defects were collected from 1986 to 2006 in our hospital from 1986 to 2006. The data of 6,397 cases of perinatal infants born at the Birth Defects Monitoring Hospital between the 28th and the 7th postpartum were collected. The total incidence of birth defects was 11.3%. The prevalence of birth defects, Bit and long term trends. Using chi-square test and time series analysis and other statistical methods to analyze the occurrence characteristics of birth defects, trends. Results: The incidence of birth defects in Fujian province tended to increase year by year (trend χ2 = 5.708, P <0.05) from 1986 to 2006. Distribution of birth defects have obvious seasonal aggregation. Conclusion: The incidence of birth defects in Fujian province is on the rise.