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以大剂量环磷酰胺(CTX)为主的预处理方案在国内外骨髓移植中已被广泛应用,其引起的HC也成为骨髓移植(BMT)的严重并发症之一。文献报导HC的发生率为O～40%,约4%的BMP患者死于HC。国内严氏曾报导1例。我们应用大剂量CTX、马(?)(?)及阿糖胞苷对12例急性白血病和1例(?)(?)(?)(?)AEBT)患者作自体骨髓移植(ABMT)的预处理,现将发生HC的临床情况及我们的体会报导如卜。材料和方法一、病例:我院1990年5月～1993年3月行ABMT的患者。男8人,女5人。年龄16～48岁。急
High-dose cyclophosphamide (CTX) -based preconditioning regimen has been widely used in bone marrow transplantation both at home and abroad, and the HC caused by it is also one of the serious complications of bone marrow transplantation (BMT). The incidence of HC is reported in the literature as O ~ 40%, about 4% of BMP patients died of HC. Yan has reported one case of domestic. We used high-dose CTX, horse (?) (?) And cytarabine for 12 cases of acute leukemia and 1 case of? AEBT? Patients with autologous bone marrow transplantation (ABMT) Treatment, the clinical situation of HC will now occur and our experience as reported Bu. Materials and methods First, the case: our hospital from May 1990 to March 1993 ABMT patients. 8 men and 5 women. Age 16 to 48 years old. anxious