临床上小垂体瘤越来越多见.常用的经蝶窦显微手术仍有许多缺点.因此,作者设计了经鼻蝶窦入路CT引导立体定向射频热凝损毁术以安全有效治疗小垂体瘤.在实验研究的基础上,临床上以该方法治疗12例小垂体瘤,操作简便安全,效果可靠满意,无长期并发症.探讨了适应症的选择和临床应用前景. Clinically small pituitary tumors are increasingly common. Common transsphenoidal sinus microsurgery still has many shortcomings. Therefore, the authors designed a transnasal sphenoid sinus approach CT-guided stereotactic radiofrequency thermal coagulation surgery to safely and effectively treat small pituitary tumors. Based on the experimental study, 12 patients with small pituitary tumors were clinically treated with this method. The operation is simple and safe, the effect is reliable and satisfactory, there is no long-term complications. The indications and clinical application prospects of the indications are discussed.