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目的:分别采用埃索美拉唑与奥美拉唑治疗消化道溃疡,对其治疗效果进行比较分析。方法:回顾分析我院治疗的37例消化道溃疡患者临床资料,对其实施埃索美拉唑治疗,并将患者作为观察组对象;另择取同期同症患者37例作为对照组成员,给予其奥美拉唑进行治疗;分析两种用药治疗方式临床疗效。结果:观察组总体治疗有效率为91.89%;对照组整体治疗有效率为79.39%;明显观察组更高,P<0.05;观察组腹痛消失时间更短,两组比较差异显著,P<0.05;本次患者不良反应发生率较小,仅对照组患者中有1例出现便秘情况;观察组Hp根除率可达97.30%;对照组Hp根除率为83.78%,观察组根除情况显著优于对照组,P<0.05。结论:埃索美拉唑与奥美拉唑临床治疗消化道溃疡效果良好,但对比两组治疗效率,埃索美拉唑更为显著,可以有效缩短患者腹痛消失时间,临床运用具有推广价值。
Objective: To treat esophageal peptic ulcer with esomeprazole and omeprazole, respectively, and compare their therapeutic effect. Methods: The clinical data of 37 patients with peptic ulcer treated in our hospital were retrospectively analyzed. The patients were treated with esomeprazole and the patients were taken as the observation group. Another 37 patients with symptomatic patients were selected as the control group, The omeprazole treatment; analysis of two kinds of drug treatment of clinical efficacy. Results: The overall treatment effective rate was 91.89% in the observation group and 79.39% in the control group. The observation group was significantly higher (P <0.05). The disappearance time of the abdominal pain in the observation group was shorter, with significant difference between the two groups (P <0.05) The incidence of adverse reactions in this patient is small, only one case of patients with constipation in the control group; Hp eradication rate was 97.30% in the observation group; Hp eradication rate was 83.78% in the control group, the observation group eradication was significantly better than the control group , P <0.05. Conclusion: The effects of esomeprazole and omeprazole in the treatment of peptic ulcer are good. However, esomeprazole is more effective than esomeprazole, which can effectively shorten the disappearance time of abdominal pain in patients. The clinical application has the promotion value.