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婴幼儿的人疱疹病毒6型(HHV-6)感染几乎是全球性的,但其病程、并发症及持续性或再活化的特征仍然不明。作者报道了对上述问题的研究结果。 研究对象为1990年7月～1993年7月患急性疾病至急诊室就诊的2 587例3岁以下的婴幼儿。同时选择352例年龄、性别及发病季节与其配对的无急性疾病、发热或感染的婴幼儿为对照组。HHV-6感染经外周血单核细胞培养、血清学试验及PCR检测证实。经病毒血症或血清转化证实为原发性HHV-6感染者共160例。对照组儿童的单核细胞培养无HHV-6生长。
Infants and young human herpes virus type 6 (HHV-6) infections are almost global, but their duration, complications, and persistent or reactivated features remain unknown. The authors report the results of the above study. The subjects were 2 587 infants and children under 3 years of age who were admitted to the emergency room for acute diseases from July 1990 to July 1993. At the same time, 352 infants and children with fever, fever or infection were selected as the control group. HHV-6 infection by peripheral blood mononuclear cell culture, serological tests and PCR test confirmed. A total of 160 cases of primary HHV-6 infection were confirmed by viremia or seroconversion. Monocytes from control children had no HHV-6 growth.