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国际癌症研究机构(IARC)已将氯乙烯列为对人致癌的化学物质。英、美、西德、挪威、匈牙利等国学者对接触氯乙烯工人外周血淋巴细胞染色体畸变的研究表明,长期接触100—1000ppm氯乙烯时畸变率增加,表现有染色单体和染色体的断裂、互换。接触低浓度1—15ppm氯乙烯时,未见到染色体异常。近几年来细胞遗传学的研究证明了高等生物细胞有丝分裂中姐妹染色单体交换(SCE)数目,因受到各种外来因素
The International Agency for Research on Cancer (IARC) has classified vinyl chloride as a chemical that is carcinogenic to humans. Chromosomal aberrations in peripheral blood lymphocytes exposed to vinyl chloride workers in Britain, the United States, West Germany, Norway, Hungary and other countries have shown that when the long-term exposure to vinyl chloride 100-1000ppm, the distortion rate increases, showing chromatid and chromosomal breakage, exchange. Chromosome abnormalities were not seen when exposed to low concentrations of 1-15 ppm vinyl chloride. In recent years, studies on cytogenetics have proved that the number of sister chromatid exchange (SCE) in higher biological cells during mitosis is affected by various external factors