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目的:回顾性分析13例原发性甲状旁腺功能亢进症(PHPT)患者的临床资料,探讨PHPT的误诊原因和诊治策略。方法:收集2002-2012年13例PHPT患者的资料,分析其首发症状、实验室检查及影像学表现。患者均行手术治疗,术后随访3～24个月,平均12.2个月。结果:13例患者(12例甲状旁腺腺瘤和1例甲状旁腺增生)手术均获成功,术后血钙恢复正常,骨骼及泌尿系症状缓解。结论:PHPT首发症状多为骨型和肾型。PTH(血钙)升高、B超(CT)及ECT定位是诊断该病的重要依据。手术切除病变的甲状旁腺组织是该病最有效的治疗方式。
Objective: To retrospectively analyze the clinical data of 13 patients with primary hyperparathyroidism (PHPT) and explore the causes of misdiagnosis and diagnosis and treatment strategies of PHPT. Methods: Thirteen cases of PHPT from 2002 to 2012 were collected and their initial symptoms, laboratory tests and imaging findings were analyzed. Patients underwent surgical treatment, followed up for 3 to 24 months, an average of 12.2 months. Results: Thirteen patients (12 cases of parathyroid adenoma and 1 case of hyperplasia of parathyroid gland) were successfully operated. The postoperative serum calcium returned to normal and the symptoms of bone and urinary tract were relieved. Conclusion: The first symptom of PHPT mostly bone and kidney type. PTH (serum calcium) increased, B ultrasound (CT) and ECT positioning is an important basis for the diagnosis of the disease. Surgical removal of diseased parathyroid tissue is the most effective treatment for the disease.