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WT_1基因于1990年发现,在某些组织中特异表达,它的蛋白质产物在转录调控中起一种双向转录因子作用。它自身表达也受很多因素的调控。本文综述了近年来国内外关于WT_1基因在转录调控方面的作用的研究进展。
The WT1 gene was discovered in 1990 and is specifically expressed in some tissues. Its protein product acts as a bidirectional transcription factor in transcriptional regulation. Its own expression is also regulated by many factors. This review summarizes the research progress of WT1 gene in transcriptional regulation at home and abroad in recent years.