目的探讨发现间期癌的特点,寻求提高乳腺普查效果的方法。方法总结淮安市第二人民医院2006年06月01日至2011年06月30日期间发现间期癌的普查间期、患者年龄、距离上次普查的时间间隔、间期癌的临床症状、彩超和钼靶表现、病理特点。结果间期癌7例,占同时期普查癌总量的21.9%。间期癌的发现距离上次普查的时间间隔平均为8.7个月。2例患者皮肤出现青紫,1例患者乳头溢血,4例患者乳腺隐痛而就诊。7例中5例超声探及可疑恶性肿块,3例钼靶有异常。肿瘤最大径均小于2cm,浸润性导管癌4例,导管内乳头状瘤局部癌变(浸润性)1例,髓样癌伴大量淋巴细胞浸润1例,小管癌1例,腋窝淋巴结均未见癌转移,病理分期均为Ⅰ期。结论间期癌的发现距离上次普查的时间间隔平均为8.7个月,最短6个月,彩超对于间期癌的发现优于钼靶,说明若能缩短彩超的普查间期到1年之内,可以提高普查效果,且不增加患者的放射损害。 Objective To explore the characteristics of intercostal cancer and seek ways to improve the effect of breast census. Methods The Second People’s Hospital of Huai’an City between June 01, 2006 and June 30, 2011 found that the interval between the screening of cancer, the patient’s age, the time interval from the last census, the clinical symptoms of intercostal cancer, ultrasound And molybdenum target performance, pathological features. Results of 7 cases of intercostal cancer, accounting for 21.9% of the same period the total number of census cancer. The interval from the last census of an interval cancer was found to be 8.7 months on average. Two patients showed bruising on the skin, one patient had nipple hemorrhage, and four patients had pain in the breast. Among the 7 cases, 5 cases were detected by ultrasound and suspicious malignant tumor, and 3 cases had abnormal molybdenum target. The largest diameter of tumor were less than 2cm, invasive ductal carcinoma in 4 cases, intraductal papilloma local carcinogenesis (invasive) in 1 case, medullary carcinoma with a large number of lymphocytic infiltration in 1 case, 1 case of small duct cancer, axillary lymph nodes were not seen Metastasis, stage of the disease are Ⅰ. Conclusion The interval between the last screening and the last screening is 8.7 months and the shortest is 6 months. The detection of metaphase cancer by color Doppler ultrasound is better than that of molybdenum target, which shows that if the shortening of the census period of color Doppler ultrasound to within 1 year , Can improve the census results, and does not increase the patient’s radiation damage.