杀灭菊酯是一种人工合成的拟除虫菊酯杀虫剂,现广泛用以控制农业和储粮害虫,以及传播疾病与危害牲畜的昆虫。据报道职业性接触杀灭菊酯可引起麻木、瘙痒、烧灼感等皮肤感觉异常,但无红斑、水肿、起疱和其它任何皮肤刺激症状。为证实杀灭菊酯的这种作用,作者进行了双盲试验,比较局部应用杀灭菊酯工业品、杀灭菊酯重尾馏分及乙醇(载体)后受试者的皮肤感觉。前两种物质皆用乙醇稀释180倍。男女受试者共36人。一周内分三次在 Pyrethrins, a synthetic pyrethroid insecticide, are widely used to control agricultural and stored grain pests and to spread disease and harms insects. Occupational exposure to fenpropathrin has been reported to cause numbness, itching, burning and other skin sensations but without erythema, edema, blistering and any other skin irritation. To confirm this effect of fenpropathrin, the authors conducted a double-blind trial comparing the topical application of fenvalerate industrial products to the skin sensation of subjects after fenpropylate heavy ends and ethanol (vehicle) were sacrificed. The first two substances are diluted 180 times with ethanol. A total of 36 men and women subjects. Three times in a week