论文部分内容阅读
他汀类药物为羟甲基戊二酸单酰辅酶A(HMG-CoA)还原酶的特异性竞争抑制剂,可减少胆固醇的生物合成,使血胆固醇水平降低。细胞内胆固醇含量减少又可刺激细胞表面低密度脂蛋白(LDL)受
Statins are specific competitive inhibitors of hydroxymethyl glutaryl coenzyme A (HMG-CoA) reductase, which reduces cholesterol biosynthesis and decreases blood cholesterol levels. Reduced intracellular cholesterol levels in turn can stimulate cell surface low density lipoprotein (LDL) receptors