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目的 :研究白虎追风丸对佐剂性关节炎 (AA)大鼠滑膜细胞分泌肿瘤坏死因子 α(TNF α)的影响。方法 :采用消化分离的方法获得滑膜细胞 ,放免法检测原代大鼠滑膜细胞培养上清液中TNF α的水平。结果 :白虎追风丸可明显下调AA大鼠滑膜细胞分泌TNF α的水平。
Objective : To study the effect of Baihu Zipong Pill on the secretion of tumor necrosis factor α (TNF α) from synoviocytes of adjuvant arthritis (AA) rats. Methods : Synovial cells were obtained by digestion and separation. The levels of TNF α in primary cultured rat synoviocytes were measured by radioimmunoassay. RESULTS: Baihu Zhanfeng Pills could significantly down-regulate the levels of TNFα secreted by synoviocytes of AA rats.