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目的观察阿昔洛韦联合甲钴胺片治疗带状疱疹后遗神经痛的临床效果。方法选择2012年2月—2013年8月我院收治的带状疱疹后遗神经痛患者36例,将其随机分成对照组和观察组,各18例。两组患者均给予基础治疗,对照组仅单纯给予阿昔洛韦进行治疗,观察组给予阿昔洛韦联合甲钴胺片进行治疗,观察两组患者临床疗效、疼痛消失时间及治疗过程中不良反应情况。结果观察组患者总有效率为94.4%,不良反应发生率为5.6%,疼痛消失时间为(2.48±1.57)d。对照组患者总有效率为72.2%,不良反应发生率为22.2%,疼痛消失时间为(4.52±3.64)d。观察组患者总有效率高于对照组,不良反应发生率低于对照组,疼痛消失时间短于对照组(P<0.05)。结论阿昔洛韦联合甲钴胺片治疗带状疱疹后遗神经痛疗效确切,不良反应少,疼痛消失快。
Objective To observe the clinical effect of aciclovir combined with mecobalamin in the treatment of postherpetic neuralgia. Methods From February 2012 to August 2013, 36 cases of postherpetic neuralgia patients admitted to our hospital were randomly divided into control group and observation group, with 18 cases in each group. The two groups were given basic treatment, the control group was treated with acyclovir alone, the observation group was given acyclovir combined with mecobalamin tablets for treatment, the two groups of patients with clinical efficacy, pain disappear time and treatment of poor Reaction situation. Results The total effective rate in the observation group was 94.4%, the adverse reaction rate was 5.6% and the pain disappear time was (2.48 ± 1.57) d. The total effective rate of the control group was 72.2%, the incidence of adverse reactions was 22.2% and the pain disappear time was (4.52 ± 3.64) d. The total effective rate in the observation group was higher than that in the control group, the incidence of adverse reactions was lower than that in the control group, and the disappearance time of pain was shorter than that of the control group (P <0.05). Conclusion Aciclovir combined with methylcobalamin tablets for the treatment of postherpetic neuralgia curative effect is accurate, less adverse reactions, pain disappeared quickly.