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目的研究我院上报的药物不良反应(ADR)发生特点及规律,为临床合理安全用药提供参考。方法对我院2009年1月1日～2011年12月31日发生的365例药物不良反应进行回顾性统计分析。结果 365例ADR报表中,男性171(46.85%)略低于女性194(53.15%);在年龄分布方面,年龄21～40岁与年龄≤20岁的青少年ADR发生率较高;ADR发生时间在10～30min内较多;由抗菌药物导致的ADR最多(60.27%);静脉滴注方式引起的ADR最多(81.64%);涉及系统以皮肤及附件损伤最为常见(41.64%)。结论医务人员应高度重视不良反应工作,提高不良反应的预防与救治能力,减少ADR发生。
Objective To study the characteristics and laws of adverse drug reaction (ADR) reported in our hospital so as to provide a reference for clinical rational and safe drug use. Methods A retrospective statistical analysis of 365 cases of adverse drug reactions occurred in our hospital from January 1, 2009 to December 31, 2011 was performed. Results Among 365 cases of ADR, 171 (46.85%) were slightly lower than 194 (53.15%) in women. In terms of age distribution, the incidence of ADR was higher in adolescents aged 21-40 years and <20 years. The incidence of ADR was The most ADR was caused by antibacterial drugs (60.27%). The most ADR was caused by intravenous drip (81.64%). The damage of skin and accessory was the most common (41.64%). Conclusion Medical staff should attach great importance to adverse reactions, improve the prevention and treatment of adverse reactions, and reduce the occurrence of ADR.