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本文报告用含阿霉素(或表阿霉素)为主的联合化疗方案治疗小细胞肺癌的近期疗效。本组病例共41例,男性31例,女性10例。年龄从27至66岁,中位数49岁。41例中用CA(或E)P方案20例,EA(或E)P方案21例,总有效率为61％(25/41),其中CR9.8％(4/41),局限型为80％,CR15.0％,广泛型42.9％,CR4.8％。本组病例治疗结果显示有效率与病期、年龄和治疗周期数有关,局限型高于广泛型,ⅡⅢa期高于Ⅲb、Ⅳ期,随着年龄增加疗效似有提高,化疗周期数增加,疗效提高,但有局限性。
This article reports the short-term efficacy of a combination chemotherapy regimen containing doxorubicin (or epirubicin) in the treatment of small cell lung cancer. There were 41 cases in this group, 31 males and 10 females. Ages range from 27 to 66 years and the median is 49 years old. Forty-one patients had CA (or E)P regimen in 20 cases and EA (or E)P regimen in 21 cases. The total effective rate was 61% (25/41), of which CR was 9.8% (4/41). The limitation was 80%, CR 15.0%, extensive 42.9%, CR 4.8%. The treatment results in this group showed that the efficacy was related to the stage of disease, age, and the number of treatment cycles. The type of limitation was higher than that of the extensive type. The stage IIIa was higher than stage IIIb and IV. With the increase of age, the curative effect seemed to increase, and the number of cycles of chemotherapy increased. Improve but have limitations.