论文部分内容阅读
本文对高血压心脏病34例,以二维及多普勒超声和放射免疫测定法观察卡托普利治疗前后其LVM和血浆AⅡ浓度的变化。证明卡托普利长程治疗可使82.4%(28/34例)的患者的LVM有不同程度的消退,且约半效由LVH逆转为正常。并发现LVM的消退与血浆AⅡ浓度的下降幅度密切相关(r=0.812)。显示卡托普利对高心病LVM的消退作用与其对RAS生成AⅡ的抑制作用有关。
In this paper, 34 cases of hypertensive heart disease, two-dimensional and Doppler ultrasound and radioimmunoassay before and after treatment with captopril LVM and plasma concentrations of AII changes. It was proved that captopril long-term treatment can make LVM regress to some extent in 82.4% (28/34 cases) and return to normal from LVH about half. The regression of LVM was found to be closely related to the decrease of plasma AII concentration (r = 0.812). It showed that Captopril’s regressive effect on LVM with high heart disease was related to the inhibitory effect on AAS induced by RAS.