本科收治一例先天性唇裂伴鼻咽癌患者,临床少见,予以报道。聂某,男,31岁,煤矿岩石工人。1989年10月起常有鼻咽涕中带血丝,1990年1月左上颈部出现包块,继而伴有轻度头痛,于1990年3月8日入院。有先天性唇裂腭裂,12岁时已行唇裂修复术。嗜烟15年,偶然饮酒。家族中无唇裂腭裂及肿瘤患者。体检:一般情况尚可。颅神经体征阴性。左上唇裂修复术后畸形,左上硬软腭全裂,软腭裂缝宽达2.5cm,鼻咽顶后壁充分暴露,直观可见。鼻咽粘膜潮红充血,顶后壁偏左有约2cm×2cm范围莱花状新生物,呈紫红色。左侧全颈四个大小肿块,大者约2cm× Undergraduate admitted a case of congenital cleft lip with nasopharyngeal carcinoma patients, clinical rare, be reported. Nie Mou, male, 31 years old, rock mine workers. In October 1989 there were frequent bloody nasopharyngeal tears in January 1990, the upper left neck mass, followed by mild headache, admitted on March 8, 1990. Congenital cleft lip and cleft palate, cleft lip repair has been performed at the age of 12. Cigarette smoking 15 years, occasionally drinking. Family without cleft lip and cleft palate and cancer patients. Physical examination: the general situation is acceptable. Negative cranial nerve signs. Left upper cleft lip repair deformity, the upper left hard palate cracked, soft palate crack width of 2.5cm, nasopharyngeal posterior wall fully exposed, intuitively visible. Nasopharyngeal mucosal flushing hyperemia, the top left posterior wall of about 2cm × 2cm range of new flower-like creature, was purple. The left side of the neck four size of the tumor, the largest about 2cm ×