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本文以回顾性方式对我院内科1995年9月至11月共1600个出院患者进行了调查,其中抗生素使用1155例,使用率72.18％,使用最广泛的是青霉素,占使用人数的52.46％,头孢类占12.35％,奎诺酮类占6.58％.治疗用药617人次,占53.45％,预防用药538人,占46.55％,其中依据细菌培养及药取用药共297人次,占25.71％,联合使用抗生素557人次,占48.27％,更换使用抗生素684人,占59.27％。从这些结果看,抗生素的使用存在着不合理应用及滥用情况:应用范围广,盲目用药多,联合用药指征宽。这势必造成耐药菌株的产生和临床疗效差,增加患者的痛苦和经济负担。
This retrospective review of our department of internal medicine from September 1995 to November a total of 1,600 discharged patients were investigated, including the use of antibiotics in 1155 cases, the use rate of 72.18%, the most widely used is penicillin, accounting for 52.46% of the number of users, Cephalosporins accounted for 12.35%, quinolones accounted for 6.58% .Treatment of 617 people, accounting for 53.45%, preventive medicine 538, accounting for 46.55%, of which 297 were based on bacterial culture and drug use, accounting for 25.71%, combined use 557 antibiotics, accounting for 48.27%, replacing 684 antibiotics, accounting for 59.27%. From these results, the use of antibiotics there are unreasonable use and abuse: a wide range of applications, blind use of drugs, combined with a wide range of indications. This will inevitably lead to the emergence of drug-resistant strains and poor clinical efficacy, increase the patient’s pain and financial burden.