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目的:探讨正常形态精子百分率对体外受精-胚胎移植(IVF-ET)治疗结局的影响。方法:回顾分析于本中心接受治疗的238个IVF-ET周期,根据WHO推荐的Diff-Quik染色方法及评价标准进行精子形态学分析,共分为三组:A组:5%<正常形态精子百分率≤10%,B组:10%<正常形态精子百分率<15%,C组:正常形态精子百分率≥15%,比较各组精子形态与IVF-ET治疗结局的关系。结果:各组间女方年龄、不孕年限、男方年龄、女方基础FSH值、Gn天数、Gn总量、hCG日E2值、hCG日P值、内膜厚度、获卵总数、MⅡ卵数等结果比较均无显著性差异(P>0.05),三组患者的受精率、2PN受精率、多精受精率、2PN卵裂率、可移植胚胎率、优质胚胎率、着床率、妊娠率、流产率、多胎率等均无显著性差异(P>0.05)。结论:当正常形态精子百分率>5%时,精子形态对常规IVF的治疗结局没有影响。
Objective: To investigate the effect of the percentage of normal morphology sperm on the outcome of IVF-ET. Methods: 238 cycles of IVF-ET treated in our center were retrospectively analyzed. According to the WHO Diff-Quik staining method and evaluation criteria, sperm morphological analysis was divided into three groups: Group A: 5% The percentage of sperm was less than 10% in group B, 10% in normal group, 15% in normal group and 15% in normal group. The relationship between sperm morphology and IVF-ET treatment outcome in each group was compared. Results: The results showed that there was no significant difference in the age of female, the age of infertility, the age of male, the female FSH, the number of Gn, the total Gn, the day of hCG, the daily value of hCG, the thickness of intima, (P> 0.05). The fertilization rate, 2PN fertilization rate, fertilization rate, 2PN cleavage rate, transplanting embryo rate, high quality embryo rate, implantation rate, pregnancy rate, abortion Rate, multiple birth rate and so no significant difference (P> 0.05). CONCLUSIONS: Sperm morphology had no effect on the treatment outcome of conventional IVF when the percentage of normal spermatozoa was> 5%.