摘要加拿大全国乳腺癌筛查研究(CNBSS)25年的随访资料表明乳腺钼靶筛查并没有降低乳腺癌死亡率。这种结果该如何解释。在进行了系统的文献检索和描述性分析后,我们认为本次实验中也许忽略了一个重要细节:受访的全部乳腺癌病例中,68%的肿瘤是可以触及的,在这种情况下,检测早期筛查是否有价值没有意义。触诊之后进行的随机化使得 Summary 25-year follow-up data from the National Breast Cancer Screening Study (CNBSS) in Canada indicate that breast mammography screening did not reduce breast cancer mortality. How to interpret this result? After conducting a systematic literature search and descriptive analysis, we think that one important detail that may have been overlooked in this experiment was that 68% of all breast cancer cases were palpable. In such cases, There is no point in detecting the value of early screening. Randomization after palpation results in